Journal articleAuthors : Gerlinger, Patrick D. (2023)
Engineering modular type I polyketide synthases (PKS) for the targeted incorporation of non-natural
15 substrates to create variations in the polyketide backbone is a long-standing goal of PKS research. Thus far,
16 most approaches focused on engineering the acyltransferase domain (AT) of PKS, whereas the effects of
17 other ubiquitous domains such as the ketosynthase domain (KS) have received much less attention. In this
18 work, we&#... 
