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  • OER000002352.pdf.jpg
  • Journal Article

  • In vitro reconstitution of the M.tb proteasome core particle reveals conserved aspects of bacterial proteasome assembly

    • Authors : Kante, Anupama (2023)

  • According to the WHO, one in three people in the world has a latent tuberculosis infection. Tuberculosis is caused by the bacterium Mycobacterium tuberculosis (M.tb). The development of multi-drug resistant (MDR) tuberculosis indicates a need for novel treatments. Hence, it is important to find a second line of treatment for patients infected with MDR tuberculosis. The proteasome is known to be necessary for survival under stress and pathogenicity i...