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Journal article

Cell-free Expression of Proton-Coupled Folate Transporter in the Presence of Nanodiscs

Authors : Do, Hoa Quynh (2021)

The Proton-Coupled Folate Transporter (PCFT) is a transmembrane transport protein that controls the absorption of dietary folates in the small intestine. PCFT also mediates uptake of chemotherapeutically used antifolates into tumor cells. PCFT has been identified within lipid rafts observed in phospholipid bilayers of plasma membranes, a micro environment that is altered in tumor cells. The present study aimed at investigating the ...