Journal articleAuthors : Sawant, Anupam A. (2023)
RNA-based genetic code is thought to be central to life’s emergence due to its dual ability for information transfer and catalysis. Nonetheless, the genetic code of early life was potentially not restricted to canonical genetic alphabets alone. The presence of an extensive repertoire of modified nucleobases in extant biology as ‘signatures of the past’, highlights the relevance of non-canonical alphabets, ably strengthened by experiments demonstrating their r... 
