Journal articleAuthors : Mühleip, Alexander (2023)
Mitochondrial energy conversion requires an intricate architecture of the inner
23 mitochondrial membrane1. Here we show that in ciliates, the membrane curvature is
24 provided by a supercomplex containing all four respiratory chain components. We report
25 cryo-electron microscopy and cryo-tomography structures of the supercomplex that
26 comprises 150 different proteins and 311 bound lipids, forming a stable 5.8-megadalton
27 assembly. Due to ...