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  • OER000002676.pdf.jpg
  • Journal article


  • Authors : Mühleip, Alexander (2023)

  • Mitochondrial energy conversion requires an intricate architecture of the inner 23 mitochondrial membrane1. Here we show that in ciliates, the membrane curvature is 24 provided by a supercomplex containing all four respiratory chain components. We report 25 cryo-electron microscopy and cryo-tomography structures of the supercomplex that 26 comprises 150 different proteins and 311 bound lipids, forming a stable 5.8-megadalton 27 assembly. Due to ...