Journal ArticleAuthors : McBride, John M. (2023)
Alteration of one or few amino acid residues can affect
structure [1–3] and function [4] of a protein and, in extreme
cases, be the difference between health and disease [5, 6].
Understanding structural consequences of point mutations
is important for drug design [7, 8] and could also accelerate
optimization of enzymatic function via directed evolution
[9, 10]. In these and other applications, theoretical
models [11] could... 
