Journal ArticleAuthors : Böken, Dorothea (2023)
The hyperphosphorylation and aggregation of the microtubule binding protein tau plays a key
role in the development of Alzheimer’s disease and other tauopathies, ultimately resulting in
the formation of intracellular tau filaments. While the structure of the filaments formed in
humans has recently been determined to atomic resolution, there is far less information
available about the smaller aggregates formed in earlier stages of th...