Duyệt theo

Hồ sơ tác giả

Tìm kiếm theo: Chủ đề tinh thể học

Duyệt theo: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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  • OER000002609.pdf.jpg
  • Journal article

  • Ambient temperature crystal structure of Escherichia coli CyaY protein displays alternate conformation

    • Tác giả : Shafiei, Alaleh (2023)

  • Frataxin is a 23 KDa mitochondrial iron-binding protein that is involved in biogenesis of iron sulfur clusters. A deficiency in frataxin leads to Friedreich's ataxia, a progressive neurodegenerative disorder. The bacterial ortholog of eukaryotic mitochondrial frataxin, CyaY, is thought to play a role in iron sulfur cluster assembly as an iron supplier, making it an important target for study. Here, we present the first ambient tem...
  • OER000002918.pdf.jpg
  • Journal article

  • Molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox

    • Tác giả : Rutbeek, Nicole R. (2021)

  • Streptococcus pyogenes, or Group A Streptococcus, is a Gram-positive bacterium that 4 can be both a human commensal and pathogen. Central to this dichotomy are temperate 5 bacteriophages that incorporate into the bacterial genome as a prophage. These genetic 6 elements encode both the phage proteins as well as toxins harmful to the human host. 7 One such conserved phage protein paratox (Prx) is always found enco...
  • OER000002357.pdf.jpg
  • Journal Article

  • Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila

    • Tác giả : Penner, Tiffany V. (2023)

  • Legionella are freshwater Gram-negative bacteria that in their normal environment infect protozoa. However, this adaptation also allows Legionella to infect human alveolar macrophages and cause pneumonia. Central to Legionella pathogenesis are more than 330 secreted effectors, of which there are 9 core effectors that are conserved in all pathogenic species. Despite their importance, the biochemical function of several core effectors remains unclear. ...