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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kumar, Arun HS | - |
| dc.date.accessioned | 2024-01-05T04:06:35Z | - |
| dc.date.available | 2024-01-05T04:06:35Z | - |
| dc.date.issued | 2021 | - |
| dc.identifier.other | OER000003004 | vi |
| dc.identifier.uri | http://dlib.hust.edu.vn/handle/HUST/23868 | - |
| dc.description.abstract | Recombinant neprilysin due to its degradation potential against Amyloid-β (Aβ) peptides has been looked at as a potential therapeutic candidate for treating Alzheimer’s disease (AD). However the enzymatic activity of neprilysin against different Aβ peptides can variable which significantly limits the therapeutic optimization. Using the molecular interaction analysis and modelling it against the known enzyme-substrate kinetics, this study developed a novel approach to predicting biosimilar enzyme-substrate kinetics. | vi |
| dc.description.uri | https://www.biorxiv.org/content/10.1101/2021.03.25.436981v1.full.pdf+html | vi |
| dc.format | vi | |
| dc.language.iso | en | vi |
| dc.publisher | bioRxiv | vi |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Vietnam | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/vn/ | * |
| dc.subject | Mô hình hóa | vi |
| dc.subject | peptide Amyloid-β | vi |
| dc.subject | bệnh Alzheimer | vi |
| dc.subject | Neprilysin | vi |
| dc.subject.lcc | TP437 | vi |
| dc.title | Modelling the efficacy of Neprilysin from various species in degrading different Amyloid-β peptides: Potential application in therapeutics of Alzheimer’s disease | vi |
| dc.type | Journal article | vi |
| dc.description.note | CC BY 4.0 | vi |
| Appears in Collections: | OER - Kỹ thuật hóa học; Công nghệ sinh học - Thực phẩm; Công nghệ môi trường | |
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