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dc.contributor.authorFracchiolla, Dorotea-
dc.contributor.authorChang, Chunmei-
dc.contributor.authorHurley, James H-
dc.date.accessioned2024-04-23T02:27:31Z-
dc.date.available2024-04-23T02:27:31Z-
dc.date.issued2020-
dc.identifier.otherOER000000801vi
dc.identifier.urihttp://dlib.hust.edu.vn/handle/HUST/24540-
dc.descriptionTài liệu này được phát hành theo giấy phép CC-BY -ND 4.0vi
dc.description.abstractAutophagy requires the synthesis of PI(3)P and the conjugation of LC3 to the phagophore membrane. We reconstituted these two reactions and their coupling by WIPI2, and showed that positive feedback between PI3KC3-C1 and WIPI2 leads to rapid LC3 lipidation by the ATG16L1 complex.vi
dc.description.urihttps://www.biorxiv.org/content/10.1101/2019.12.18.880591v3vi
dc.formatPDFvi
dc.language.isoenvi
dc.publisherBiochemical Journalvi
dc.rightsAttribution-NoDerivs 3.0 Vietnam*
dc.rights.urihttp://creativecommons.org/licenses/by-nd/3.0/vn/*
dc.subjectAutophagyvi
dc.subjectLysosomesvi
dc.subjectAutophagosomesvi
dc.subject.lccQD405vi
dc.titleA PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagyvi
dc.typeJournal articlevi
Appears in Collections:OER - Kỹ thuật hóa học; Công nghệ sinh học - Thực phẩm; Công nghệ môi trường

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