Browsing by Author Dandamudi, Mowgli

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  • OER000002783.pdf.jpg
  • Journal article

  • Authors : Dandamudi, Mowgli (2023)

  • FMRFamide and similar neuropeptides are important physiological modulators in most invertebrates, but the molecular basis of FMRFamide activity at its receptors is unknown. We therefore sought to identify the molecular determinants of FMRFamide potency in one of its native targets, the excitatory FMRFamide-gated sodium channel (FaNaC) from gastropod mollusks. Using molecular phylogenetics and electrophysiological measurement of function, we identified a broad FaNaC family t...