Journal articleAuthors : M.M., Kutuzov; E.A., Belousova; T.A., Kurgina (2020)
Include base excision repair (BER) is implemented by a cellular signal PARylation catalysed by PARP1 and PARP2. Despite intensive studies, it is far from clear how BER is regulated by PARPs and how the roles are distributed between the PARPs. Here, we investigated the effects of PARP1, PARP2 and PARylation on activities of the main BER enzymes (APE1, Pol and LigIII) in combination with XRCC1 in the nucleosomal context. We constructed...