Browsing by Author Jacob, Shancy P

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  • OER000000847.pdf.jpg
  • Journal article

  • Authors : Sumanth, Mosale Seetharam; Jacob, Shancy P; Abhilasha, Kandahalli Venkataranganayaka (2020)

  • Alpha-1-acid glycoprotein (AGP-1) is a positive acute phase glycoprotein with uncertain functions. Serum AGP-1 (sAGP-1) is primarily derived from hepatocytes and circulates as 12 to 20 different glycoforms. We isolated a glycoform secreted from stimulated human neutrophils (nAGP-1). Its peptide sequence was identical to hepatocyte-derived sAGP-1, but nAGP-1 differed from sAGP-1 in its chromatographic behaviour, electrophoretic mobility, and glycosylation. The function of these&#...