Browsing by Author Lacobucci, Claudio

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  • OER000000696.pdf.jpg
  • Journal article

  • Authors : Tüting, Christian; Lacobucci, Claudio; Lhling, Christian H (2020)

  • The ribosome is not only a highly complex molecular machine that executes translation according to the central dogma of molecular biology, but also an exceptional specimen for testing and optimizing cross-linking/mass spectrometry (XL-MS) workflows. Due to its high abundance, ribosomal proteins are frequently identified in proteome-wide XL-MS studies of cells or cell extracts. Here, we performed in-depth cross-linking of the E. coli ribosome using the amine-r...