Browsing by Author Nadzieja, Marcin

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  • OER000000851.pdf.jpg
  • Journal article

  • Authors : Björnsdotter, Emilie; Nadzieja, Marcin; Chang, Wei (2020)

  • Faba bean is a widely adapted and high-yielding legume cultivated for its protein-rich seeds1. However, the seeds accumulate the anti-nutritional pyrimidine glucosides vicine and convicine, which can cause haemolytic anaemia—favism—in the 400 million individuals genetically predisposed by a deficiency in glucose-6-phosphate dehydrogenase2. Here, we identify the first enzyme associated with vicine and convicine biosynthesis, which we name VC1. We show that VC1 co-locates wit...