Browsing by Author Naik, Mandar T

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  • OER000000805.pdf.jpg
  • Journal article

  • Authors : Ryan, Veronica H; Perdikari, Theodora Myrto; Naik, Mandar T (2020)

  • mRNA transport in neurons is a ubiquitous process but has been often overlooked as a contributor to disease. Mutations of transport granule protein hnRNPA2 cause hereditary proteinopathy of neurons, myocytes, and bone. Here, we examine transport granule component specificity, assembly/disassembly, and the link to neurodegeneration. hnRNPA2 transport granule components hnRNPF and ch-TOG interact weakly with hnRNPA2 yet they each partition specifically into hnRNPA2 liqui...