Journal articleAuthors : Saad, Hamada (2023)
Lasso peptides are a class of ribosomally synthesized and post-translationally modified peptides (RiPPs)
that feature an isopeptide bond and a distinct lariat fold. A growing number of secondary modifications have been
described that further decorate lasso peptide scaffolds. Using genome mining, we have discovered a pair of lasso
peptide biosynthetic gene clusters (BGCs) that include cytochrome P450 genes. Here, we report the structural
characterizat... 
