Browsing by Author Walsh, Brenna J. C

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  • OER000000793.pdf.jpg
  • Journal article

  • Authors : Capdevila, Daiana A; Walsh, Brenna J. C; Zhang, Yifan (2020)

  • Cysteine thiol-based transcriptional regulators orchestrate coordinated regulation of redox homeostasis and other cellular processes by “sensing” or detecting a specific redox-active molecule, which in turn activates the transcription of a specific detoxification pathway. The extent to which these sensors are truly specific in cells for a singular class of reactive small molecule stressors, e.g., reactive oxygen or sulfur species, is largely unknown. Here we report...