Browsing by Subject Na+/H+

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  • Authors : Agustín, Pablo Hernansanz (2023)

  • The mitochondrial electron transport chain (mETC) converts the energy of substrate oxidation into a H+ electrochemical gradient (Δp), which is composed by an inner mitochondrial membrane (IMM) potential (ΔΨmt) and a pH gradient (ΔpH). So far, ΔΨmt has been assumed to be composed exclusively by H+. Mitochondrial Ca2+ and Na+ 15 homeostasis, which are essential for cellular function, are controlled by exchangers and antiporters in the inner mitochondrial&#...