Browsing by Subject Nab2

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  • OER000000150.pdf.jpg
  • Periodicals (Báo – Tạp chí)

  • Authors : Corgiat, Edwin B. (2020)

  • The human ZC3H14 gene, which encodes a ubiquitously expressed polyadenosine zinc finger RNA binding protein, is mutated in an inherited form of autosomal recessive, non-syndromic intellectual disability. To gain insight into ZC3H14 neurological functions, we previously developed a Drosophila melanogaster model of ZC3H14 loss by deleting the fly ortholog, Nab2. Studies in this invertebrate model reveal that Nab2 controls final patterns of neuron projection within f...