Journal articleAuthors : Watson, James A. (2023)
Spalt-like 4 (SALL4) maintains vertebrate embryonic stem cell identity and is required for the
development of multiple organs, including limbs. Mutations in SALL4 are associated with Okihiro
syndrome and SALL4 is also a known target of thalidomide. SALL4 protein has a distinct preference
for AT-rich sequences, recognised by a pair of zinc fingers at the C-terminus. However, unlike many
characterised zinc finger proteins, SALL4 shows flexibl...