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Showing results 1 to 20 of 103
  • OER000002338.pdf.jpg
  • Journal Article


  • Authors : Buchanan, Jane L. (2023)

  • Tryptophan is an essential amino acid that is extensively characterized as a regulator of cellular function through its metabolism by indoleamine 2,3-deoxygenase (IDO) into the kynurenine pathway. However, despite decades of research on tryptophan metabolism, the metabolic regulatory roles of it and its metabolites are not well understood. To address this, we performed an activity metabolomics screen of tryptophan and most of its known metabolit...

  • OER000002281.pdf.jpg
  • Journal Article


  • Authors : Orsburn, Benjamin C. (2023)

  • A recent study demonstrated a substantial signal increase when employing a 0.5% acetic acid buffer additive instead of the traditional 0.1% formic acid used in shotgun proteomics. In this study I compare these two buffers for a dilution series of tryptic digests down to 20 picograms peptide on column on a TIMSTOF single cell proteome (SCP) system. I observe a comparable relative level of signal increase as previously reported...

  • OER000002953.pdf.jpg
  • Journal article


  • Authors : Ten, Tensho (2021)

  • Mint3 is known to enhance aerobic ATP production, known as the Warburg effect, by binding to FIH-1. Since this effect is considered to be beneficial for cancer cells, the interaction is a promising target for cancer therapy. However, previous research has suggested that the interacting region of Mint3 with FIH-1 is intrinsically disordered, which makes investigation of this interaction challenging. Therefore, we adopted a physicochemical approach that co...

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  • Authors : Nguyễn Thị Thu;  Advisor : Trương Thị Ngọc Liên (2019)

  • Tổng quan cảm biến sinh học, ung thư tiền liệt tuyến, màng đơn lớp tự lắp ghép, công nghệ polyme in phân tử chế tạo đầu thu sinh học nhân tạo, một số kỹ thuật phân tích. Thực nghiệm quy trình chế tạo cảm biến sử dụng đầu thu sinh học nhân tạo PSA-MIP. Kết quả đặc trưng quang phổ râmn, cảm biến PSA-MIP@pp1, PSA-MIP@pp2.

  • OER000002661.pdf.jpg
  • Journal article


  • Authors : McFadden, Emily J. (2023)

  • The lncRNA Second Chromosome Locus Associated with Prostate 1 (SChLAP1) was previously identified as a predictive biomarker and potential driver of aggressive prostate cancer. Recent work suggests that SChLAP1 may bind the SWI/SNF chromatin remodeling complex to promote prostate cancer metastasis, though the exact role of SWI/SNF recognition is debated. To date, there are no detailed biochemical studies of apo SChLAP1 or SChLAP1:protein com...

  • OER000001858-1.pdf.jpg
  • Ebooks (Sách điện tử)


  • Authors : Khalil, Islam A. (2020)

  • Nanomedicine refers to the use of nanotechnological applications in biomedical fields such as therapeutics, diagnostics, monitoring, visualization, tissue engineering and even surgery. This book presents recent updates in the nanomedicine market and discusses several aspects of drug delivery and tissue regeneration using different platforms and devices.

  • OER000002718.pdf.jpg
  • Journal article


  • Authors : Pedram, Kayvon (2023)

  • Targeted protein degradation is an emerging strategy for the elimination of classically undruggable proteins. Here, to expand the landscape of substrates that can be selectively degraded, we designed degraders which are dependent on both peptide sequence and glycosylation status of the target protein. We applied this approach to mucins, O-glycosylated proteins that drive cancer progression through biophysical and immunological mechanisms. Engineering of&...

  • OER000001857-1.pdf.jpg
  • Ebooks (Sách điện tử)


  • Authors : Srivastava, Ruby (2020)

  • Nano-scale technologies is an emerging field of electronics on the scale of a billionth of a meter with integrated mechanical, fluidic, optical, and biological components. These technologies require less space, construction material, less expense, and are easy to transport and store with applications in optical communications, nanocomputing, sensors, and biomedical devices. The electronic applications include silicon photonics, adaptive MEMS, VLSI design and applications, o...

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  • Authors : Vũ Quang Hưng;  Advisor : Nguyễn Đức Thuận (2019)

  • Nghiên cứu tổng quan về thiết bị theo dõi bệnh nhân. Nghiên cứu về thiết bị theo dõi bệnh nhân đa thông số MP600N. Thiết kế, xây dựng và triển khai hạ tầng mạng cho hệ thống theo dõi bệnh nhân trung tâm tại Bệnh viện Tai Mũi Họng Trung Ương

  • OER000002291.pdf.jpg
  • Journal Article


  • Authors : Bennett, Grace M. (2023)

  • Aberrant cellular phosphorylation is a hallmark of several diseases including inflammation and cancers (1–3). Protein phosphorylation is a post-translational modification that can act as a switch to regulate biochemical pathways and is regulated by the concerted action of two classes of enzymes: kinases and phosphatases. As such, kinases and phosphatases present as significant potential clinical molecular targets. To date, several kinase inhibitors have&#...

  • OER000002467.pdf.jpg
  • Journal Article


  • Authors : Marien, Jules (2023)

  • The microtubule-associated protein (MAP) tau plays a key role in the regulation of microtubule assembly and spatial organisation. Tau hyperphosphorylation affects its binding on the tubulin surface and has been shown to be involved in several pathologies such as Alzheimer disease. As the tau binding site on the microtubule lays close to the disordered and highly flexible tubulin C-terminal tails (CTTs), these are likely to impact ...

  • E00000000217.pdf.jpg
  • Ebooks (Sách điện tử)


  • Authors : Nguyễn Đức, Thuận; Vũ Duy, Hải; Nguyễn Phan, Kiên (2023)

  • Giới thiệu về nguồn gốc và đặc trưng của tín hiệu y sinh, mạch khuếch đại thuật toán, mạch khuếch đại điện sinh học, mạch lọc tương tự, một số mạng ứng dụng trong y sinh, giới thiệu về nhiễu trong mạch xử lý tín hiệu, số tín hiệu y sinh và một số cấu kiện điện tử ứng dụng trong kỹ thuật xử lý tín hiệu y sinh hiện nay. Cuốn sách được biên soạn thành 8 chương, trong đó: Chương 1...