Browsing by Subject UFL1-UFC1

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  • OER000002657.pdf.jpg
  • Journal article

  • Authors : Banerjee, Sayanika (2023)

  • Ufmylation, a protein modification by Ubiquitin-like (UBL) protein UFM1, plays a crucial role in several cellular processes including DNA damage response, protein translation and ER homeostasis. To date, little is known how the enzymes responsible for this modification coordinate their action. Here we have studied the details of UFL1 (E3) activity, its binding to UFC1 (E2), and its relation to UBA5 (E1), using a combination of structur...