Browse

Author Profile

Browsing by Subject COVID-19

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 8 to 9 of 9
  • OER000000775.pdf.jpg
  • Journal article

  • Structural interactions between pandemic SARS-CoV-2 spike glycoprotein and human Furin protease

    • Authors : Vankadari, Naveen (2020)

  • The SARS-CoV-2 pandemic is an urgent global public health emergency and warrants investigating molecular and structural studies addressing the dynamics of viral proteins involved in host cell adhesion. The recent comparative genomic studies highlight the insertion of Furin protease site in the SARS-CoV-2 spike glycoprotein alerting possible modification in the viral spike protein and its eventual entry to host cell and presence of Furin site implicated to...
  • OER000000166.pdf.jpg
  • Periodicals (Báo – Tạp chí)

  • The repurposed drugs suramin and quinacrine inhibit cooperatively in vitro SARS-CoV-2 3CLpro

    • Authors : Eberle, Raphael J. (2020)

  • The causative agent of COVID-19 (SARS-CoV-2) has spread worldwide resulting in a pandemic of unprecedented magnitude. To date, no clinically safe drug or vaccine is available and the development of molecules to combat SARS-CoV-2 infections is imminent. A well-known strategy to identify molecules with inhibitory potential against SARS-CoV-2 proteins is the repurposing of clinically developed drugs, e.g., anti-parasitic drugs. The results described in this study dem...