Browse

Author Profile

Browsing by Subject N-acyl-phosphatidylethanolamine phospholipase D (NAPE-PLD)

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 1 of 1
  • OER000000831.pdf.jpg
  • Journal article

  • Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D

    • Authors : Aggarwal, Geetika; Zarrow, Jonah E; Mashhadi, Zahra (-)

  • N-acyl-phosphatidylethanolamine phospholipase D (NAPE-PLD) (EC 3.1.4.4) catalyzes the final step in the biosynthesis of N-acyl-ethanolamides (NAEs). Reduced NAPE-PLD expression and activity may contribute to obesity and inflammation, but a major obstacle to elucidating the role of NAPE-PLD and NAE biosynthesis in various physiological processes has been the lack of effective NAPE-PLD inhibitors. The endogenous bile acid lithocholic acid (LCA) inhibits NAPE-PLD activity (IC50...