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Browsing by Subject s Nuclear Cap Binding Proteins · messenger ribonucleoproteins (mRNPs)

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  • OER000000726.pdf.jpg
  • Journal article

  • Affinity proteomic dissection of the human nuclear cap-binding complex interactome

    • Authors : Dou, Yuhui; Kalmykova, Svetlana; Pashkova, Maria (2020)

  • A 5’, 7-methylguanosine cap is a quintessential feature of RNA polymerase II-transcribed RNAs, and a textbook aspect of co-transcriptional RNA processing. The cap is bound by the cap-binding complex (CBC), canonically consisting of nuclear cap-binding proteins 1 and 2 (NCBP1/2). The CBC has come under renewed investigative interest in recent years due to its participation in RNA-fate decisions via interactions with RNA productive factors as well as ...