Browsing by Subject Nucleocapsid protein

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  • OER000000382.pdf.jpg
  • Periodicals (Báo – Tạp chí)


  • Authors : Perdikari, Theodora Myrto; Murthy, Anastasia C; Ryan, Veronica H (2020)

  • Tightly packed complexes of nucleocapsid protein and genomic RNA form the core of viruses and may assemble within viral factories, dynamic compartments formed within the host cells. Here, we examine the possibility that the multivalent RNA-binding nucleocapsid protein (N) from the severe acute respiratory syndrome coronavirus (SARS-CoV-2) compacts RNA via protein-RNA liquid-liquid phase separation (LLPS) and that N interactions with host RNA-binding proteins are mediat...