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  • Ebooks (Sách điện tử)


  • Authors : Monteverde, Gay (-)

  • 1, 2, 3 Write! retains a basic structure, several exercises and tables, and some nicely written explanations from Writing for Success, but about 75% of the original 96,000-word text was cut. Then, information on mechanics, expanded writing process steps, example readings, and a glossary was added. Chapters were organized to reflect a 1, 2, 3-step process, moving from words to sentences to paragraphs to essays. 1, 2, 3, Write! is desi...

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  • Book


  • Authors : Thạc, Bình Cường (2023)

  • Cuốn sách trình bày chi tiết kiến thức về các kỹ năng mềm cần thiết trong học tập, làm việc và cuộc sống hằng ngày như kỹ năng giao tiếp, thuyết trình, làm việc nhóm, lập kế hoạch và quản lý thời gian, viết email, đọc sách, v.v..

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  • Ebooks (Sách điện tử)


  • Authors : - (2023)

  • Hội thảo quốc tế lần thứ 15 “Hệ thống thông minh - 2022” (INTELS'22) được tổ chức vào ngày 14-16 tháng 12 năm 2023 tại Viện Hàn lâm Khoa học Nga, Moscow, Nga. Đây là một sự kiện hai năm một lần với lịch sử ba mươi năm. INTELS'22 tập trung vào các lĩnh vực hệ thống thông minh và trí tuệ nhân tạo, các khía cạnh lý thuyết và ứng dụng của chúng vào sự phát triển bền vững. Hầu hết&#...

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  • Book


  • Authors : - (2019)

  • This book provides insights into models and theoretical backgrounds, important properties, characterizations and applications of 2D materials, including graphene, silicon nitride, aluminum nitride, ZnO thin film, phosphorene and molybdenum disulfide.

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  • Journal Article


  • Authors : Buchanan, Jane L. (2023)

  • Tryptophan is an essential amino acid that is extensively characterized as a regulator of cellular function through its metabolism by indoleamine 2,3-deoxygenase (IDO) into the kynurenine pathway. However, despite decades of research on tryptophan metabolism, the metabolic regulatory roles of it and its metabolites are not well understood. To address this, we performed an activity metabolomics screen of tryptophan and most of its known metabolit...

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  • Ebooks (Sách điện tử)


  • Authors : Von, Herausgegeben (2022)

  • The year 2019 marked the 300th anniversary of Daniel Defoe's Robinson Crusoe. His novel was a huge success right away and was soon followed by bootlegs and translations. With the robinsonade, an independent genre of adventure literature was born. These contributions examine the novel within the context of bookselling history, provide new interpretations, and shed light on its multifaceted adaptation history up into the twenty-first century.

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  • Journal article


  • Authors : Srinivas, Pooja  (2023)

  • Acquired ribosomal RNA (rRNA) methylation has emerged as a significant mechanism of aminoglycoside resistance in pathogenic bacterial infections. Modification of a single nucleotide in the ribosome decoding center by the aminoglycoside-resistance 16S rRNA (m7G1405) methyltransferases effectively blocks the action of all 4,6-deoxystreptamine ring-containing aminoglycosides, including the latest generation of drugs. To define the molecular basis of 30S subunit recognition ...

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  • Ebooks (Sách điện tử)


  • Authors : Antonio Hernández, Bejarano (2018)

  • Cuốn sách này sẽ giới thiệu các khái niệm chính cần thiết để viết trò chơi 3D bằng thư viện LWJGL 3. LWJGL là một thư viện Java cung cấp quyền truy cập vào các API gốc được sử dụng để phát triển các ứng dụng đồ họa (OpenGL), âm thanh (OpenAL) và điện toán song song (OpenCL). Thư viện này tận dụng hiệu suất cao của các ứng dụng OpenGL gốc khi sử dụng ngôn ngữ Java. Mục tiêu ban đầu ...

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  • Ebooks (Sách điện tử)


  • Authors : Lenssen, Philipp (2006)

  • This book, in a way, is born out of my daily weblog “Google Blogoscoped” (blog.outer-court.com) and those who read it. Since 2003 I’ve been writing there covering all things Google – not just the fun stuff, but news, discussion, interviews, tutorials, and everything beyond with a relation to search engines. Thanks to those reading along and providing pointers or feedback, I’ve been able to discover more interesting pag...

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  • Ebooks (Sách điện tử)


  • Authors : - (2016)

  • Triển vọng 5G - đổi mới và ứng dụng là tập hợp các nghiên cứu và phát triển gần đây trong lĩnh vực Công nghệ di động thế hệ thứ năm (5G), tương lai của truyền thông không dây. Rất nhiều ý tưởng và kiến ​​thức mới về 5G được trình bày trong cuốn sách này cũng như các ứng dụng đa dạng từ khoa học sức khỏe đến khoa học sức khỏe. mô hình kinh doanh. Các tác giả của các chương khá...

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  • Journal article


  • Authors : Mullally, Grace; Aelst, Kara van; Naqvi, Mohsin M (2020)

  • A key aim in exploiting CRISPR-Cas is the engineering of gRNA to introduce additional functionalities, ranging from small nucleotide changes that increase efficiency of on-target binding to the inclusion of large functional RNA aptamers and ribonucleoproteins (RNPs. Interactions between gRNA and Cas9 are crucial for RNP complex assembly but several distinct regions of the gRNA are amenable to modification. Using a library of modified gRNAs, we used in&#x...

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  • Journal article


  • Authors : Franziska, Holz (2021)

  • Carbon Capture and Storage (CCS) might be a central technology to reach the decarbonisation goals of the European energy system. However, CCS deployment faces multiple economic, technological, and infrastructure challenges. Related literature tends to only focus on certain aspects of the CCS technology or to be limited to a particular sector perspective. In contrast, this paper presents a holistic modelling framework to analyse the longterm ...

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  • Journal article


  • Authors : Ghomi, Fatemeh Ashari; Kittilä, Tiia; Welner, Ditte Hededam (2020)

  • UDP-dependent glycosyltransferases (UGTs) are enzymes that glycosylate a wide variety of natural products, thereby modifying their physico-chemical properties, i.e. solubility, stability, reactivity, and function. To successfully leverage the UGTs in biocatalytic processes, we need to be able to screen and characterise them in vitro, which requires efficient heterologous expression in amenable hosts, preferably Escherichia coli. However, many UGTs are insoluble when expressed in...

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  • Journal Article


  • Authors : Daly, Leonard A. (2023)

  • Protein tyrosine sulfation (sY) is a post-translational modification (PTM) catalysed by Golgi-resident Tyrosyl Protein SulfoTransferases (TPSTs). Information on protein tyrosine sulfation is currently limited to ~50 human proteins with only a handful having verified sites of sulfation. The contribution of this chemical moiety for the regulation of biological processes, both inside and outside the cell, remains poorly defined, in large part due to analytica...

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  • Journal article


  • Authors : Lorton, Benjamin M; Harijan, Rajesh K; Burgos, Emmanuel S (2020)

  • Using highly accurate quantitative binding analysis combined with high-resolution crystal structures of WDR5 in complex with unmodified (me0) and me1/me2s L-Arginine amino acids and in complex with H3R2me1 peptide, we provide a rigorous biochemical study of this important biological interaction. Despite modest structural differences at the binding interface, our study supports an interaction model regulated by a binary arginine methylation switch: H3R2me2a prevents int...

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  • Journal article


  • Authors : Kim, C. (2023)

  • Orthosteric inhibition of kinases has been challenging due to the conserved active site architecture of kinases and emergence of resistance mutants. Simultaneous inhibition of distant orthosteric and allosteric sites, which we refer to as “double-drugging”, has recently been shown to be effective in overcoming drug resistance. However, detailed biophysical characterization of the cooperative nature between orthosteric and allosteric modulators has not be...

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  • Journal article


  • Authors : Raeburn, Candice B. (2021)

  • An extensive network of chaperones and other proteins maintain protein homeostasis and guard against inappropriate protein aggregation that is a hallmark of neurodegenerative diseases. Using a fluorescence resonance energy-based biosensor that simultaneously reports on intact cellular chaperone holdase activity and detrimental aggregation propensity, we investigated the buffering capacity of the systems managing protein homeostasis in the nucleus of the human cell l...