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  • Thesis


  • Authors : Pham Thi Kim Thanh;  Advisor : Mai Anh Tuan (2011)

  • Trình bày tổng quan về năng lượng được sản xuất, tiêu thụ và nhu cầu cấp thiết phát triển năng lượng thay thế mới và nguồn năng lượng tái tạo. Pin mặt trời, các tính chất của vật liệu và các kỹ thuật chế tạo màng Cu2ZnSnS4. Tính toán lý thuyết khe năng lượng của cấu trúc Cu2ZnSnS4, hệ thống phun phủ nhiệt. Tổng hợp các kết quả thu được từ phổ nhiễu xạ tia X, ảnh từ kính hiển vi điện&#x...

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  • Journal Article


  • Authors : Krishnarjuna, Bankala (2023)

  • The detergent-free isolation of membrane proteins using synthetic polymers is becoming the desired approach for functional and structural studies of membrane proteins. Since the expression levels for many membrane proteins are low and a high yield of functionalized reconstituted membrane proteins is essential for in vitro studies, it is crucial to optimize the experimental conditions for a given polymer to effectively solubilize target membranes/...

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  • Journal Article


  • Authors : Ziegler, Alexander R. (2023)

  • Proteases comprise approximately 3% of the human genome and catalyse the cleavage of pepKde bonds1. Proteolysis is essenKal for maintaining protein homeostasis, altering substrate structure, funcKon, and localisaKon2. Proteases contribute to vital cellular funcKons such as cell growth and repair3, immune signalling4, and wound healing5,6; dysregulated protease acKviKes underpin numerous pathological condiKons including cancer, inflammaKon neurodegeneraKon, and gastrointesKnal diseases7. Knowle...

  • OER000000341.pdf.jpg
  • Book


  • Authors : Elsa Tsioumani (2020)

  • This book explores the emergence and development of the legal concept of fair and equitable benefit-sharing, and its application in agriculture. Developed in the 1990s, the concept of fair and equitable benefit-sharing has been deployed in an ever-wider variety of international instruments, including those on biodiversity, climate change, and human rights. A lack of clarity persists however on what fair and equitable benefit-sharing requires and entails, and&...

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  • Book


  • Authors : Tanweer Akram; Salim Rashid (2020)

  • This open access book seeks to foster a multidisciplinary understanding of the ties between faith, financial intermediation, and economic progress by drawing on research across economics, finance, history, philosophy, ethics, theology, public policy, law, and other disciplines. Chapters in this edited volume examine themes as consequential as economic opportunities, real world outcomes and faith; values and consumerism; faith, financial intermediation and economic development&#x...

  • OER000000910.pdf.jpg
  • Journal article


  • Authors : Atkinson, Joshua T; Jones, Alicia M; Nanda, Vikas (2020)

  • To investigate whether adenylate kinase (AK) homologs differ in their functional tolerance to mutational lesions that alter dynamics, we subjected three homologs having a range of thermostabilities to random circular permutation and evaluated where new protein termini were non-disruptive to activity using a cellular selection and deep mutational scanning. Analysis of the positional tolerance to new termini, which increase local conformational entropy by breaking peptid...

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  • Journal article


  • Authors : Matzinger, Manuel; Kandioller, Wolfgang; Doppler, Philipp (2020)

  • Cross-linking mass spectrometry is an increasingly used, powerful technique to study protein-protein interactions or to provide structural information. Due to sub-stochiometric reaction efficiencies, cross-linked peptides are usually low abundant. This results in challenging data evaluation and the need for an effective enrichment. Here we describe an improved, easy to implement, one-step method to enrich azide-tagged, acid-cleavable disuccinimidyl bis-sulfoxide (DSBSO) cross...

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  • Journal article


  • Authors : Harder, Oliver F.  (2023)

  • Observing proteins as they perform their tasks has largely remained elusive, which has left our understanding of protein function fundamentally incomplete. To enable such observations, we have recently proposed a novel technique that improves the time resolution of cryo-electron microscopy (cryo EM) to microseconds. Here, we demonstrate that microsecond time-resolved cryo-EM enables observations of fast protein dynamics. We use our approach to elucidate&#...

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  • Ebooks (Sách điện tử)


  • Authors : - (2020)

  • This book covers the broad topic of structural integrity of non-metallic materials, considering the modelling, assessment, and reliability of structural elements of any scale. Original contributions from engineers, mechanical materials scientists, computer scientists, physicists, chemists, and mathematicians are presented, applying both experimental and theoretical approaches.

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  • Professional Practice Paper


  • Authors : Oemer, Gregor; Hammel, Forrest A.; Janetzko, John (2020)

  • The molecular assembly of cells depends not only on their balance between anabolism and catabolism, but to a large degree also on the building blocks available in the environment. For cultivated mammalian cells, this is largely determined by the composition of the growth medium used. Here we study the impact of medium lipids on mitochondrial membrane architecture and function by combining LC-MS/MS lipidomics and functional tests with lipid supp...

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  • Journal article


  • Authors : Shannon, A; Selisko, B; Le, NTT (2020)

  • The ongoing Corona Virus Disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has emphasized the urgent need for antiviral therapeutics. The viral RNA-dependent-RNA-polymerase (RdRp) is a promising target with polymerase inhibitors successfully used for the treatment of several viral diseases. Here we show that Favipiravir exerts an antiviral effect as a nucleotide analogue through a combination of chain termination, slow...

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  • Periodicals (Báo – Tạp chí)


  • Authors : Sarkar, Anindita; Carter, Eric L; Harland, Jill B (2020)

  • Rev-Erbβ is a nuclear receptor that couples circadian rhythm, metabolism, and inflammation.1-7 Heme binding to the protein modulates its function as a repressor, its stability, its ability to bind other proteins, and its activity in gas sensing.8-11 Rev-Erbβ binds Fe3+-heme tighter than Fe2+-heme, suggesting its activities may be regulated by the heme redox state.9 Yet, this critical role of heme redox chemistry in defining the protein’s resting state&#x...

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  • Book


  • Authors : - (-)

  • The purpose of this book is to offer the results of several researches on ferroelectricity, cov‐ ering a wide range of topics on ceramics, polymers, thin films, ferroelectric liquids, compo‐ sites, ferroelectricity at nanoscale, and also on multiferroic systems. The book has been the result of an important number of contributions of researchers from the international scientif‐ ic community

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  • Ebooks (Sách điện tử)


  • Authors : Kuei Liaw, Shien- (2019)

  • The chapters in this edited volume are by scholars/experts working in academia in Taiwan, Egypt, Israel, Germany and Japan. The contents are intended to provide a common forum for researchers, scientists and engineers throughout the world to exchange ideas and gain knowledge in the areas of fiber sensing technologies. The scope of the book includes the following chapters: 1. Introductory Chapter: An Overview of the Methodologies and Applications...