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  • Book

  • La transformation des grains

    • Authors : Jean-François Cruz; D. Joseph Hounhouigan; Michel Havard (2020)

  • This book covers several aspects of grain processing and complements the book on grain preservation in the same collection. It presents different processing methods, targeting mainly small and medium-sized enterprises as the main players in food processing systems in the South countries.
  • OER000001638.pdf.jpg
  • Book

  • Lab-on-a-Chip Fabrication and Application

    • Authors : - (2016)

  • The necessity of on-site, fast, sensitive, and cheap complex laboratory analysis, associated with the advances in the microfabrication technologies and the microfluidics, made it possible for the creation of the innovative device lab-on-a-chip (LOC), by which we would be able to scale a single or multiple laboratory processes down to a chip format. The present book is dedicated to the LOC devices from two points of view: LOC fabrication and...
  • OER000002405.pdf.jpg
  • Journal Article

  • Label-free quantification LC-mass spectrometry proteomic analysis of blood plasma in healthy dogs

    • Authors : Doulidis, Pavlos G. (2023)

  • Bloodwork is a widely used diagnostic tool in veterinary medicine, as diagnosis and therapeutic 15 interventions often rely on blood biomarkers. However, biomarkers available in veterinary medicine 16 often lack sensitivity or specificity. Mass spectrometry (MS)-based proteomics technology has been 17 extensively used in biological fluids and offers excellent potential for a more comprehensive 18 characterization of the plasma proteome in veterinary medicine. In this&#...
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  • Journal Article

  • Label-free Quantification of Host-Cell Protein Impurity in a Recombinant Hemoglobin Reference Material

    • Authors : Henrion, André (2023)

  • Quantitative analysis depends on pure-substance primary calibrators with known mass fractions of impurity. Here, label-free quantification (LFQ) is being evaluated as a readily available, reliable method for determining the mass fraction of host-cell proteins (HCPs) in bioengineered proteins. For example, hemoglobin-A2 (HbA2) is being used as obtained through overexpression in E.coli. Two different materials had been produced: natural, and U-15N-labeled HbA2. For quantification&...
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  • Journal article

  • Laboratory evolution identifies elongated flavodoxins that support electron transfer to sulfite reductases

    • Authors : Truong, Albert (2023)

  • Flavodoxins (Flds) mediate the flux of electrons between oxidoreductases in diverse metabolic pathways. While dozens of Fld-partner oxidoreductases have been discovered, these only represent a subset of the oxidoreductases that couple with ferredoxin (Fd) protein electron carriers. To investigate whether Flds can support electron transfer to a sulfite reductase (SIR) that evolved to couple with a Fd, we evaluated the ability of Flds to tra...
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  • Journal article

  • Lack of astrocytic glycogen alters synaptic plasticity but not seizure susceptibility

    • Authors : Duran, Jordi; Brewer, M. Kathryn (2020)

  • Brain glycogen is mainly stored in astrocytes. However, recent studies both in vitro and in vivo indicate that glycogen also plays important roles in neurons. By conditional deletion of glycogen synthase (GYS1), we previously developed a mouse model entirely devoid of glycogen in the central nervous system (GYS1Nestin-KO). These mice displayed altered electrophysiological properties in the hippocampus and increased susceptibility to kainate-induced seizures. To underst...
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  • Ebooks (Sách điện tử)

  • Lagoon Environments Around the World

    • Authors : - (2021)

  • Lagoon Environments Around the World - A Scientific Perspective covers a wide range of topics. Typically bordering between land and sea, lagoons are among the most diversely utilized waterways on the planet. Lagoons are extremely important environments socio-economically, and their usage places ever increasing stress on these very sensitive aquatic regions. The effective management of shallow aquatic environments requires a detailed scientific understanding of the ...
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  • Book

  • Landscape Reclamation: Rising From What’s Left

    • Authors : - (2020)

  • This is especially true for previously developed sites, currently abandoned or underused. Instead of consuming green lands, these derelict landscapes need to be redeveloped and given new life, enabling their transition to an increasingly sustainable urban setting. In this scenario, the present book, considers a set of subjects that highlight the diverse nature of the scientific domains associated with landscape reclamation, emphasizing the need to acknowledge ...
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  • Ebooks (Sách điện tử)

  • Landscapes of Investigation Contributions to Critical Mathematics Education

    • Authors : Penteado, Miriam Godoy (2022)

  • The book Landscapes of Investigation: Contributions to Critical Mathematics Education was planned, written, and edited during a difficult period of time. The Coronavirus pandemic haunted the world with devastating implications, also for the professional and private lives of the authors of this book. Furthermore, the time was difficult for the two of us, due to Ole’s health problems. However, in spite of all difficulties, the book ...
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  • Ebooks (Sách điện tử)

  • Language and Culture in Context - A Primer on Intercultural Communication

    • Authors : Jones, Godwin- (2023)

  • The text introduces some of the key concepts in intercultural communication as traditionally presented in (North American) courses and textbooks, namely the study of differences between cultures, as represented in the works and theories of Edward Hall and Geert Hofstede. Common to these approaches is the prominence of context, leading to a view of human interactions as dynamic and changeable, given the complexity of language and culture, as human&#x...
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  • Journal article

  • Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and function

    • Authors : Good, Nathan M; Fellner, Matthias; Demirer, Kemal (2020)

  • The presence of lanthanide elements (Ln3+) and pyrroloquinoline quinone (PQQ) containing cofactors in XoxF methanol dehydrogenases (MDHs) and ExaF ethanol dehydrogenases (EDHs) has expanded the list of biological elements and opened novel areas of metabolism and ecology. Other MDHs known as MxaFIs are related in sequence and structure to these proteins, yet they instead possess a Ca2+-PQQ cofactor. An important missing piece of the Ln3+ puzzle is definin...
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  • Ebooks (Sách điện tử)

  • Large language models in cybersecurity : threats, exposure and mitigation

    • Authors : - (2024)

  • Cuốn sách truy cập mở này cung cấp cho những người thực hành an ninh mạng kiến ​​thức cần thiết để hiểu những rủi ro khi ngày càng có nhiều mô hình ngôn ngữ lớn (LLM) mạnh mẽ và cách giảm thiểu chúng. Nó cố gắng vượt qua những kẻ tấn công độc hại bằng cách dự đoán những gì chúng có thể làm. Nó cũng cảnh báo các nhà phát triển LLM hiểu những rủi ro trong công việc của họ đối v...
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  • Ebooks (Sách điện tử)

  • Large-scale column-free purification of bovine F-ATP synthase

    • Authors : Chimari, Jiko (2023)

  • Mammalian F-ATP synthase is central to mitochondrial bioenergetics and is present in the inner mitochondrial membrane in a dynamic oligomeric state of higher oligomers, tetramers, dimers and monomers. In vitro investigations of mammalian F-ATP synthase are often limited by the ability to purify the oligomeric forms present in vivo at sufficient quantity, stability and purity. We developed a purification approach for the isolation of bovine ...
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  • Journal article

  • Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity

    • Authors : Jones, Bryan J; Evans III, Robert L; Mylrea, Nathan J (2020)

  • Hydroxynitrile lyases (HNL’s) belonging to the α/β-hydrolase-fold superfamily evolved from esterases approximately 100 million years ago. Reconstruction of an ancestral hydroxynitrile lyase in the α/β-hydrolase fold superfamily yielded a catalytically active hydroxynitrile lyase, HNL1. Several properties of HNL1 differ from the modern HNL from rubber tree (HbHNL). HNL1 favors larger substrates as compared to HbHNL, is two-fold more catalytically promiscuous for ester h...
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  • Ebooks (Sách điện tử)

  • Laser Ablation - From Fundamentals to Applications

    • Authors : Itina, Tatiana (2017)

  • Shortly after the demonstration of the first laser, the most intensely studied theoretical topics dealt with laser-matter interactions. Many experiments were undertaken to clarify the major ablation mechanisms. At the same time, numerous theoretical studies, both analytical and numerical, were proposed to describe these interactions. These studies paved the ways toward the development of numerous laser applications, ranging from laser micro- and nanomachining to materi...