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  • Book


  • Authors : - (2020)

  • Complexity of human milk composition, the mechanisms underlying the beneficial effects associated with breastfeeding, and the factors and determinants involved in lactation, including its promotion and support.

  • Book


  • Authors : - (2020)

  • Biomarkers of environmental toxicants are measures of exposures, some of which can serve to assess disease risk and inter-individual susceptibilities. This collection provides a valuable update of the most recent biochemical and analytical tools that employ biomarkers in toxicology research, biomarker discovery, and exposure and risk assessment in population-based studies.

  • Book


  • Authors : - (2020)

  • Many of these compounds are well known; however, the multiple types of structures together with the variable responses depending of the type of biocontrol needed in a wide range of applications, such as clinical, agricultural, general hygiene, and food, necessitates the continuous search for specific applications and the continuous study of how to use these substances. The present book provides a summary of reviews and original research works that&#...

  • Book


  • Authors : - (2020)

  • This book aims to incorporate and introduce the advances in green technologies to the cyber-based industries. It is hoped that the novel green technologies presented in this book are useful in assisting the global community in working towards fulfilling the Sustainable Development Goals.

  • Book


  • Authors : - (2020)

  • The mycotoxigenic abilities and the subsequent introduction of harmful metabolites into the food chain. The accelerating climatic changes are resulting in pathogen population and chemotype shifts all around the world, thus increasing the demand for continuous studies of factors that affect the virulence, disease severity and mycotoxin accumulation in plant tissues. This Special Issue summarizes recent advances in the field of Fusarium genetics, biology and toxicol...

  • Journal article


  • Authors : Modenutti, Carlos P; Capurro, Juan I. Blanco; Ibba, Roberta (2020)

  • UDP-glucose:glycoprotein glucosyltransferase (UGGT) is the only known glycoprotein folding quality control checkpoint in the eukaryotic glycoprotein secretory pathway. When the enzyme detects a misfolded glycoprotein in the Endoplasmic Reticulum (ER), it dispatches it for ER retention by re-glucosylating it on one of its N-linked glycans. Recent crystal structures of a fungal UGGT have suggested the enzyme is conformationally mobile. Here, a negative stain electron mic...

  • Ebooks (Sách điện tử)


  • Authors : Mogg, Trevor J.; W. Burton, Graham (2020)

  • The influence of the peptide QAKTFLDKFNHEAEDLFYQ on the kinetics of the SARS-CoV-2 spike protein S1 binding to angiotensin-converting enzyme 2(ACE2) was studied to model the interaction of the virus with its host cell. This peptide corresponds to the sequence 24-42 of the ACE2 α1 domain, which is the binding site for the S1 protein. The on-rate and off-rate of S1-ACE2 complex formation were measured in the presence of various peptide conce...

  • Professional Practice Paper


  • Authors : Rudolph, Johannes (2020)

  • Poly(ADP-ribose) polymerase 1 (PARP1) is an important player in the response to DNA damage. Recently, histone PARylation factor (HPF1) was shown to be a critical modulator of the activity of PARP1 by facilitating PARylation of histones and redirecting the target amino acid specificity from acidic to serine residues. Here we investigate the mechanism and specific consequences of HPF1-mediated PARylation using nucleosomes as both activators and substrates for&#...