Journal articleAuthors : Banerjee, Sayanika (2023)
Ufmylation, a protein modification by Ubiquitin-like (UBL) protein UFM1, plays a crucial
role in several cellular processes including DNA damage response, protein translation and
ER homeostasis. To date, little is known how the enzymes responsible for this modification
coordinate their action. Here we have studied the details of UFL1 (E3) activity, its binding
to UFC1 (E2), and its relation to UBA5 (E1), using a combination of structur...