Journal articleAuthors : Bickers, Sarah C. (2023)
ATP binding cassette (ABC) proteins generally couple ATP hydrolysis to the active
20 transport of solutes across cellular membranes. All ABC proteins contain a core structure of two
21 transmembrane domains (TMD1, TMD2) and two nucleotide binding domains (NBD1, NBD2),
22 and many ABC proteins contain additional domains. Some members of the C subfamily of ABC
23 (ABCC) proteins, such as the multidrug resistant protein 1 (MRP1), con...