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  • Journal article


  • Authors : Bickers, Sarah C.  (2023)

  • ATP binding cassette (ABC) proteins generally couple ATP hydrolysis to the active 20 transport of solutes across cellular membranes. All ABC proteins contain a core structure of two 21 transmembrane domains (TMD1, TMD2) and two nucleotide binding domains (NBD1, NBD2), 22 and many ABC proteins contain additional domains. Some members of the C subfamily of ABC 23 (ABCC) proteins, such as the multidrug resistant protein 1 (MRP1), con...