Journal articleAuthors : DAmico, Kevin A. (2023)
Most membrane fusion reactions in eukaryotic cells are mediated by membrane tethering
17 complexes (MTCs) and SNARE proteins. MTCs are much larger than SNAREs and are thought
18 to mediate the initial attachment of two membranes. Complementary SNAREs then form
19 membrane-bridging complexes whose assembly draws the membranes together for fusion. Here,
20 we present a cryo-EM structure of the simplest known MTC, the 255-kDa Dsl1 complex... 
