Journal articleAuthors : Kumara, Niraj (2023)
Ribosome hibernation is a key survival strategy bacteria adopt under environmental stress,
where a protein, hibernation promotion factor (HPF), transitorily inactivates the ribosome and
slows down its overall protein synthesis. The mechanism is well studied in enteric bacteria,
which mainly hibernate its ribosome in 100S disome form through a dual domain, long HPF
(HPFlong) or a single domain, short HPF (HPFshort) in concert with another ri...