Journal articleAuthors : Anderson, Michael J.M. (2023)
The adhesion receptor dystroglycan provides a critical mechanical link between the extracellular matrix (ECM)
and the actin cytoskeleton to help muscle cells withstand contraction and neural cells maintain the blood brain
barrier. Disrupting the link is associated cancer and muscular dystrophy. Proteolysis of dystroglycan by matrix
metalloproteinases (MMPs) provides a mechanism to break the mechanical anchor and is amplified in several
pathogenic states,&... 
