Ebooks (Sách điện tử)Authors : Madabushi, Sowmya (2023)
Puromycin-sensitive aminopeptidase (E.C. 3.4.11.14, UniProt P55786), a zinc
6 metallopeptidase belonging to the M1 family, degrades a number of bioactive peptides as
7 well as peptides released from the proteasome, including polyglutamine. We report the
8 crystal structure of PSA at 2.3 Ǻ. Overall, the enzyme adopts a V-shaped architecture
9 with four domains characteristic of the M1 family aminopeptidases, but it is in a less
10... 
