Journal articleAuthors : Samant, Rahul S. (2023)
works in concert with co-chaperones to stabilize its client
proteins, which include multiple drivers of oncogenesis
and malignant progression. Pharmacologic inhibitors of
HSP90 have been observed to exert a wide range of
effects on the proteome, including depletion of client
proteins, induction of heat shock proteins, dissociation
of co-chaperones from HSP90, disruption of client protein
signaling networks, and recruitment of the protein
... 
