Thông tin tài liệu
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Stricklan, Kara A. | - |
dc.date.accessioned | 2023-11-22T03:43:03Z | - |
dc.date.available | 2023-11-22T03:43:03Z | - |
dc.date.issued | 2023 | - |
dc.identifier.other | OER000002686 | vi |
dc.identifier.uri | http://dlib.hust.edu.vn/handle/HUST/23550 | - |
dc.description.abstract | The NnlA enzyme from Variovorax sp. strain JS1663 degrades the linear nitramine N-23 nitroglycine (NNG)—a natural product produced by some bacteria—to glyoxylate and nitrite 24 (NO2–). Ammonium (NH4+) was predicted as the third product of this reaction. A source of non-25 heme FeII was shown to be required for initiation of NnlA activity. However, it was unclear if 26 this FeII was being used as a metallocofactor or a reductant. This study reveals that NnlA 27 contains a b-type heme cofactor. Reduction of this heme is required to initiate NnlA activity. 28 Reduction can occur either by addition of a non-heme FeII source or by reduction with dithionite. 29 Therefore, FeII is not an essential substrate for holoenzyme activity. | vi |
dc.description.uri | https://www.biorxiv.org/content/10.1101/2022.06.19.496723v1 | vi |
dc.format | vi | |
dc.language.iso | en | vi |
dc.publisher | bioRxiv | vi |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Vietnam | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/vn/ | * |
dc.subject | yếu tố heme | vi |
dc.subject | thoái biến | vi |
dc.subject | N-nitroglycine | vi |
dc.subject | NnlA | vi |
dc.subject.lcc | QH541.5 | vi |
dc.title | Reduction of a heme cofactor initiates N-nitroglycine degradation by NnlA | vi |
dc.type | Journal article | vi |
dc.description.note | CC BY-NC-ND 4.0 | vi |
Appears in Collections: | OER - Kỹ thuật hóa học; Công nghệ sinh học - Thực phẩm; Công nghệ môi trường |
Files in This Item:
This item is licensed under a Creative Commons License